Evaluation of topical bevacizumab as an adjunct to mitomycin C augmented trabeculectomy.

There was, however, a marginally statistically significant difference between the groups in regard to cystic bleb type when compared with all other types of bleb ( P = 0.043, Fisher's exact tests).

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17 Topically administered bevacizumab, alone or as an adjunct to MMC, after trabeculectomy in rabbit eyes showed a trend towards prolonged bleb survival, even though the results of this study were not statistically significant. 18 Recently, topical bevacizumab (0.25 mg) that was administered 5 times with one-week interval was shown to be useful for the success of trabeculectomy at 6-month follow-up. 19 This study investigates the safety and synergistic effect of topical bevacizumab after trabeculectomy surgery with MMC compared to standard trabeculectomy with MMC.

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