showed a trendp = 0.076
Relative to the control group, the JLT group showed a trend of improvement in the gastrointestinal tract (mean diff. = −1.84; 95% CI: −3.87 to −0.20; p = 0.076) as well as a significant reduction in constipation which persisted from week 16 (mean diff. = −2.49; 95% CI: −3.75 to −1.23; p < 0.001) to week 38 (mean diff. = −2.17; 95% CI: −3.53 to −0.82; p = 0.002) ( Table 3 ).