KPNB1-mediated nuclear import is required for motility and inflammatory transcription factor activity in cervical cancer cells.

Oncotarget · 2017 · PMC5464831 · PMID 28427184

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Although inhibiting NFkB signaling showed a trend towards reducing HeLa cancer cell migration the results were not significantly different from the control while inhibiting KPNB1 using INI-43 and inhibiting AP-1 signaling using SP600125 significantly reduced the migratory ability of cervical cancer cells (Figure 9A ).

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