Barely Significant
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Booster immunizations with DNA plasmids encoding HER-2/neu prevent spontaneous mammary cancer in HER-2/neu transgenic mice over life span.

Sci Rep · 2017 · PMC5465096 · PMID 28596550

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showed a trendno p-value reported
Although CD8 T cells showed a trend towards an increased representation in groups treated with BI, the values were not significantly different in comparison with SI.

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