Acamprosate in a mouse model of fragile X syndrome: modulation of spontaneous cortical activity, ERK1/2 activation, locomotor behavior, and anxiety.

3b ) and drug x segment interactions were only approaching significance and therefore additional post hoc analyses were not completed.

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However, pairwise comparisons failed to reach significance with FDR correction, indicating little effects of gene or drug on startle habituation in 5–7-month-old mice (Fig. 7c ).

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