The primary end point (3-point MACE plus coronary and leg revascularization) did not reach statistical significance (HR = 0.90, P = 0.09); however, it is now well recognized that peripheral vascular disease is refractory to antihypertensive, lipid-lowering, and glucose-lowering therapy ( 24 , 25 ).
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Cardiovascular Disease and Type 2 Diabetes: Has the Dawn of a New Era Arrived?
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