Cellular Stress in the Context of an Inflammatory Environment Supports TGF-β-Independent T Helper-17 Differentiation.

Cell Rep · 2017 · PMC5483510 · PMID 28614720

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The dosing of TUDCA significantly reduced the number of T cells found in the CNS at day 12 after immunization, while at that point in time the lymph node draining the immunization site showed a trend to lower Th17 cell numbers and proportions and an increase in Th1 cells ( Figures 6 C, 6D, and S6 C).

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