c-Myc is Required for BRAF^V600E-Induced Epigenetic Silencing by H3K27me3 in Tumorigenesis.

As shown in Figure 7 E, although the H3K27me3 levels were slightly higher in Braf V600E cells than Braf WT cells, the difference did not reach statistical significance, suggesting that c-Myc may inhibit the transcription of these microRNAs through an unknown mechanism, but not H3K27me3 redistribution.

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