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Attenuation of RNA polymerase II pausing mitigates BRCA1-associated R-loop accumulation and tumorigenesis.

Nat Commun · 2017 · PMC5490191 · PMID 28649985

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A cohort of BRCA2 mutation carriers exhibited similar increase in R-loop intensity as compared to non-carriers, but the difference did not reach statistical significance ( Supplementary Fig. 1 ).

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