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Prolastin, a pharmaceutical preparation of purified human alpha1-antitrypsin, blocks endotoxin-mediated cytokine release.

Respir Res · 2005 · PMC549028 · PMID 15683545

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The median concentrations of endotoxin-stimulated IL-1β levels also decreased in the presence of Prolastin but failed to reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.