Transcatheter aortic valve implantation in patients with pre-existing chronic kidney disease.

In the multivariate model, poor baseline LV function (HR [95% CI] 3.77 (1.12–12.62)) and AKI (HR [95% CI] 1.54 (0.42–5.67)) were identified as potential predictors of 1-year mortality, however did not reach statistical significance ( Table 6 ). 3.6 AKI versus non-AKI Finally, in accordance with the reporting of AKI incidence in the existing literature, we separately analysed patients according to whether they did (n = 22) or did not (n = 92) develop AKI (having excluded those established on chronic haemodialysis).

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The risk of developing AKI however may be significant in this cohort although we were unable to show this to statistical significance, but the risk of requiring new RRT following TAVI and risk of death was not significantly impacted upon by the presence of pre-existing CKD.

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