Emulsified omega-3 fatty-acids modulate the symptoms of depressive disorder in children and adolescents: a pilot study.

Child Adolesc Psychiatry Ment Health · 2017 · PMC5497377 · PMID 28690672

Europe PMC DOI

hedged sentences

0.0050

closest p · 0.1× alpha

0.0950

boldest claim

The sentences

highly significantp = 0.005actually significant

All pairwise comparisons (Conover) in the Omega-3 group showed highly significant differences from baseline (from p = 0.005 in the 2nd week to p = 0.0001 at week 12).

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showed a trendp = 0.06so close (0.05 < p ≤ 0.1)

[ 38 ] performed a 10 weeks open label trial with 8–24 years old adolescents with SSRI treatment-resistant major depressive disorder and observed a significant (40%) reduction (p < 0.001) in symptoms in those receiving a high dose of fish oil (16.2 g/day; 10.8 g EPA, 5.4 g DHA) whilst those receiving a lower dose (2.4 g/day; 1.6 g EPA, 0.8 g DHA) showed a trend towards symptom reduction (20%) (p = 0.06).

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a trend towards significancep = 0.095so close (0.05 < p ≤ 0.1)

The interaction between Treatment*Time in the Omega-3 group for two different diagnoses showed a trend towards significance for only the DD subgroup (p = 0.095).

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