Barely Significant
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Neuroendocrine Dysregulation in Irritable Bowel Syndrome Patients: A Pilot Study.

J Neurogastroenterol Motil · 2017 · PMC5503293 · PMID 28460516

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did not reach statistical significanceno p-value reported
Interestingly, after cold pressor test IBS patients had a blunted increase MSNA burst frequency (median value: +4.1 vs +7.8 bursts/min, P = 0.048; +30.1% vs +78.1%, P = 0.023) and incidence (median value: +3.3 vs +8.1 bursts/100 heart beats, P = 0.034; 15.1% vs 58.7%, P = 0.023) than HVs, while differences in changes in mean BP (median value + 10 vs +17 mmHg, P = 0.180; +13.0% vs 22.0%, P = 0.160) and heart rate (median value: +4 vs +7 bpm, P = 0.910; +7.0% vs +12.0%, P = 0.860) did not reach statistical significance.

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