In addition, our panel of HCC cell lines showed a trend of positive correlation between NP-Dvl3 to P-Dvl3 ratio and LGR5 mRNA expression.
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Dishevelled-3 phosphorylation is governed by HIPK2/PP1Cα/ITCH axis and the non-phosphorylated form promotes cancer stemness via LGR5 in hepatocellular carcinoma.
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