In contrast, 8-Br-cAMP treatment only promoted a modest rise in Cx43 S368 phosphorylation signal (Figure 1 B), which did not reach statistical significance, consistent with PKA regulating S365 and not the pS368.
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Cyclic Nucleotides Differentially Regulate Cx43 Gap Junction Function in Uterine Artery Endothelial Cells From Pregnant Ewes.
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