Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness.

We found a nominally significant association of the stop-gain variant (T allele) with lower grip strength (additive: β =−0.062 kg, P =0.018) ( Supplementary Table 9 ) although we found no evidence for any departure from an additive genetic model at this locus ( P domdev = 0.72; Supplementary Fig. 5 ).

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