Heart rate was slightly higher in MRP1 −/− LDLr −/− double knockout mice, which did not reach statistical significance (782 ±23 bpm vs. 721 ±17 bpm; n = 8–12; p = 0.08).
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Genetic disruption of multidrug resistance-associated protein 1 improves endothelial function and attenuates atherosclerosis in MRP1<sup>-/-</sup> LDLr<sup>-/-</sup> double knockout mice.
1
0.0800
0.0800