In NSCLC for example, high levels of pAKT predicted better response to TKI (gefinitinib) therapy and significantly longer time to progression in one study [ 63 ], and in another study, pAKT and pSTAT3 both showed a trend towards association with longer time to progression on gefitinib [ 64 ].
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EGFR as a prognostic biomarker and therapeutic target in ovarian cancer: evaluation of patient cohort and literature review.
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