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Natural Killer Cells from Patients with Recombinase-Activating Gene and Non-Homologous End Joining Gene Defects Comprise a Higher Frequency of CD56<sup>bright</sup> NKG2A<sup>+++</sup> Cells, and Yet Display Increased Degranulation and Higher Perforin Content.

Front Immunol · 2017 · PMC5511964 · PMID 28769923

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Furthermore, patients with SCID had fewer CD57 + NK cells than patients with other forms of TCD ( p = 0.0041), and a similar trend was also observed when compared to infant controls, although the difference did not reach statistical significance (Figure 5 B).

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