A significant negative correlation was found between the IgM responses and age for MenC and MenW, whereas a negative trend was observed for MenY (Table 2 ).
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Novel Intervention in the Aging Population: A Primary Meningococcal Vaccine Inducing Protective IgM Responses in Middle-Aged Adults.
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The TT conjugate clearly induced a booster response in the participants, since 71.6% of the persons showed highly significant increases in IgG concentrations 7 days post-vaccination (Table 1 ).