nominally significantP < 0.05
The RNA-Seq data were analyzed using a two-way ANOVA with a focus on the two main factors of Exposure (ethanol vs saline) and p53 Genotype (KO vs WT) as well as the interaction between them (Exposure x Genotype).The results indicated that 824 genes showed nominally significant main effects of Genotype (uncorrected P < 0.05), 763 genes had nominally significant main effects of Treatment (uncorrected P-value < 0.05), and 1969 genes had nominally significant interactions of Genotype x Treatment (uncorrected P-value < 0.05).