Gene expression reversal toward pre-adult levels in the aging human brain and age-related loss of cellular identity.

Testing 1078 miRNAs and 211 TF binding sites separately, we found one miRNA and 4 TFs consistently enriched across the 19 datasets for the up-down pattern, relative to up-up; however, the results were non-significant and only marginally significant compared to permutations (one-sided p = 0.56 and p = 0.069), respectively.

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