Postzygotic single-nucleotide mosaicisms contribute to the etiology of autism spectrum disorder and autistic traits and the origin of mutations.

After exclusion of parents whose children harbored reported de novo LoF germline mutations (Iossifov et al., 2014 ) or de novo small deletions, we observed that fathers transmitting missense/LoF pSNMs to probands also tend to have higher social responsiveness scale for adults (SRS‐A) scores ( P = 0.173, one‐sided Wilcoxon rank sum test), although this effect did not reach statistical significance, probably due to the small sample size of the analysis (Supp.

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