Stroma-regulated HMGA2 is an independent prognostic marker in PDAC and AAC.

Br J Cancer · 2017 · PMC5520204 · PMID 28524160

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0.0010

closest p · 0.0× alpha

0.0940

boldest claim

The sentences

highly significantP <0.001actually significant

The associations between poor prognosis and HMGA2-positivity within the whole cohort remained highly significant in multivariate analysis, including age, sex, gemcitabine treatment, grade of differentiation and clinical stage ( P <0.001) ( Table 2 ).

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a strong trendP <0.094so close (0.05 < p ≤ 0.1)

Furthermore, in the GSE21501 cohort, including 102 PDAC patients, we observed a strong trend towards shorter OS (log Rank P <0.094) for HMGA2-high patients, which remained in the Cox Proportional Hazards model (HR 1.50 (0.92–2.45 95% confidence interval); P <0.103) ( Figure 2B ).

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