Meta-analysis revealed a trend towards higher HPSE expression in the ER (+) group than in the ER (−) group, but this difference did not reach statistical significance (OR = 1.55, 95% CI = 0.91 – 2.63, P = 0.11, Figure 8 , Table 2 ).
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Elevated heparanase expression is associated with poor prognosis in breast cancer: a study based on systematic review and TCGA data.
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