The G-protein coupled receptor 56, expressed in colonic stem and cancer cells, binds progastrin to promote proliferation and carcinogenesis.

Oncotarget · 2017 · PMC5522213 · PMID 28380450

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difference was apparentno p-value reported

The greatest difference was apparent for multi-crypt ACFs, which were abundant in hGAS mice but completely suppressed in hGAS/GPR56 –/– mice (Figure 6E ).

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