a weak trendP = 0.091
3.3 Male breast cancer epitypes and polycomb regulated genes MBC tumors of the ME2 epitype displayed significantly more hypomethylated CpGs than ME1 epitype tumors (P = 0.0038, Wilcoxon test), while ME1 tumors showed a weak trend toward more hypermethylated CpGs (P = 0.091, Wilcoxon test).