Single and combined effect of retinoic acid and rapamycin modulate the generation, activity and homing potential of induced human regulatory T cells.

PLoS One · 2017 · PMC5529012 · PMID 28746369

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did not reach statistical significanceno p-value reported

Our results showed that the best results regarding number and percentage of CD4+CD25+FOXP3+ cells were obtained with 100 nM of atRA; whereas lower levels showed no difference with IL-2 and TGF-β1 alone, 10 nM enhanced the number of Treg cells, but it did not reach statistical significance, possibly due to the limited sample size.

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