4a ); apoE3 promoted a much weaker enhancement of the Aβ 42 -α7nAChR interaction at 10 nM that did not reach statistical significance (13.6 ± 7.9% increase; Fig. 4a ).
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Increased Aβ<sub>42</sub>-α7-like nicotinic acetylcholine receptor complex level in lymphocytes is associated with apolipoprotein E4-driven Alzheimer's disease pathogenesis.
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