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Detrimental Effects of Centrally Administered Angiotensin II are Enhanced in a Mouse Model of Alzheimer Disease Independently of Blood Pressure.

J Am Heart Assoc · 2017 · PMC5533006 · PMID 28428194

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In addition, as shown in Figure 5 A and 5 B, there was a trend toward an increase in cortical macrophage/microglia and superoxide levels in the angiotensin II group compared with the vehicle group in 5XFAD mice, although the difference did not reach statistical significance.

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