A role for the tfs3 ICE-encoded type IV secretion system in pro-inflammatory signalling by the Helicobacter pylori Ser/Thr kinase, CtkA.

PLoS One · 2017 · PMC5536186 · PMID 28759055

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Subsequent assay of supernatants for IL-8 cytokine secretion showed a trend towards increased levels of IL-8 in response to co-culture with the CtkA-expressing strains compared to the cagE mutants alone in all three tfs3 + strains ( Fig 3 ).

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