Extreme assay sensitivity in molecular diagnostics further unveils intratumour heterogeneity in metastatic colorectal cancer as well as artifactual low-frequency mutations in the KRAS gene.

Br J Cancer · 2017 · PMC5537488 · PMID 28618430

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did not reach statistical significanceno p-value reported

Among all RAS mutations, the p.G12V KRAS prevailed in G3-G4 tumours, although this correlation did not reach statistical significance ( Table 3 ).

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