Barely Significant
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Unique prefrontal GABA and glutamate disturbances in co-occurring bipolar disorder and alcohol dependence.

Transl Psychiatry · 2017 · PMC5538121 · PMID 28675386

Europe PMCDOI
1
hedged sentence
0.0600
closest p · 1.2× alpha
0.0600
boldest claim

The sentences

approached significanceP =0.06so close (0.05 < p ≤ 0.1)
However, when the sample was restricted to individuals who reported consuming alcohol within the 2 weeks preceding their scan ( n =31), the BD × AD interaction, signifying uniquely low levels of dACC glutamate/water in BD+AD (Cohen’s d for BD+AD vs HC=1.01), approached significance (F=3.83, P =0.06) and reached significance (F=4.21, P =0.05) once within-voxel gray matter/brain matter composition was statistically controlled; see Figure 2 .

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