Antithrombotic treatment during coronary angioplasty after failed thrombolysis: strategies and prognostic implications. Results of the RESPIRE registry.

The bleeding rate in the group given an abciximab bolus but no infusion was notably lower, in numerical terms, than in patients given a bolus plus infusion (BARC >1 of 10% versus 15%, and BARC >2 of 3.3% versus 6.3%), and there were fewer ischemic events (0% thrombosis/infarction rate versus 7.5%). In multivariate analysis for predictors of BARC >1 bleeding, femoral access and post-RA abciximab infusion were identified as predictors, and a strong trend was seen for age > 75 years (Table 7 ).

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