Comparative analysis of the EGFR, HER2, c-MYC, and MET variations in colorectal cancer determined by three different measures: gene copy number gain, amplification status and the 2013 ASCO/CAP guideline criterion for HER2 testing of breast cancer.

J Transl Med · 2017 · PMC5540452 · PMID 28764718

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closest p · 1.0× alpha

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did not reach statistical significanceP > 0.05actually significant

The genetic alterations in EGFR , HER2 , c - MYC , and MET assessed by three different criteria were almost mutually exclusive with the MSI-H status, as expected (Table 2 ) but the effects did not reach statistical significance (all P > 0.05).

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