The independent variables shown to be associated with death were increasing age (1.04 [1.01-1.07], P = 0.0055), diabetes at time of transplant (2.79 [1.44-5.41], P = 0.0024), and rejection (2.34 [1.06-5.19], P = 0.036), whereas mean tacrolimus level greater than 9 ng/mL (2.29 [0.95-5.48], P = 0.06) and sensitized patients (2.07 [0.94-4.54], P = 0.069) showed a trend toward an increased risk of death.
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High Intrapatient Variability of Tacrolimus Levels and Outpatient Clinic Nonattendance Are Associated With Inferior Outcomes in Renal Transplant Patients.
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