Barely Significant
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Capecitabine, 5-fluorouracil and S-1 based regimens for previously untreated advanced oesophagogastric cancer: A network meta-analysis.

Sci Rep · 2017 · PMC5541083 · PMID 28769123

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Although S-1 regimens also showed a lower rate of grade 3-4 hand-foot syndrome compared to capecitabine regimens (0% versus 3%), this difference did not reach statistical significance.

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