Barely Significant
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Clinically significant sub-clonality for common drivers can be detected in 26% of KRAS/EGFR mutated lung adenocarcinomas.

Oncotarget · 2017 · PMC5542222 · PMID 28501852

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showed a trendp=0.1so close (0.05 < p ≤ 0.1)
Surprisingly, sub-clonality for EGFR mutation was associated with shorter survival time (p=0.03, Figure 3B ) whereas sub-clonality for KRAS mutation only showed a trend toward shorter survival time (p=0.1, Figure 3A ).

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