Blockade of lymphangiogenesis by mF4-31C1 resulted in a trend towards higher opacity scores, although the differences did not reach statistical significance (opacity score in uninjured: 0; after 1 week: controls: 3.1 versus mF4-31C1: 3.1; after 2 weeks: controls: 2.5 versus mF4-31C1: 3.2; after 3 weeks: controls: 2.1 versus mF4-31C1: 3.0; after 4 weeks: controls: 1.7 versus mF4-31C1: 2.5; all p-values > 0.05; Fig. 2J to R ).
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Transient Ingrowth of Lymphatic Vessels into the Physiologically Avascular Cornea Regulates Corneal Edema and Transparency.
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