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Sphingosine kinase 2 inhibition synergises with bortezomib to target myeloma by enhancing endoplasmic reticulum stress.

Oncotarget · 2017 · PMC5546428 · PMID 28467788

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A similar trend towards greater trabecular volume was also observed in combination treated mice compared to those treated with bortezomib alone, although this did not reach statistical significance (Figure 8C ).

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