Reoxygenation for 6 to 18 h showed a trend for further increase, but it was not significant, while after 24 h of reoxygenation, the metastatic efficiency started to decline and following 48 h of reoxygenation, it was similar to that of the normoxic control groups [ 33 ].
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Cell type-dependent HIF1 α-mediated effects of hypoxia on proliferation, migration and metastatic potential of human tumor cells.
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