a significant trendp = 0.007
No significant effect of ECVP on mortality was observed in patients with sepsis [ n = 5121, odds ratio (OR) 1.090, 95% CI 0.941–1.263, p = 0.252] and without AKI [ n = 6131, odds ratio (OR) 1.097, 95% CI 0.945–1.274, p = 0.224], while there was a significant trend toward increased mortality from higher ECVP load in patients without sepsis [ n = 3969, odds ratio (OR) 1.36, 95% CI 1.087–1.702, p = 0.007], as illustrated in Fig. 3 .