Interestingly, in our study, T2DM patients with mean disease duration >8 years, namely T2DM patients with poor glucose control, and subjects with complications showed a trend towards suppressed TLR mRNA expression when compared to GC subjects.
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Analysis of inflammatory cytokine and TLR expression levels in Type 2 Diabetes with complications.
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Whereas a trend towards increased serum IL-10 was observed in GC and PC patients, a marginal trend towards suppressed IL-10 was observed in GCC and PCC patients, compared with NGT (Fig. 1E ).