Decreased high density lipoprotein cholesterol is an independent predictor for persistent organ failure, pancreatic necrosis and mortality in acute pancreatitis.

In contrast to the results for TG, LDL-C, and TG/HDL-C ratio quartiles, there was a negative trend for the association across increasing HDL-C quartiles and incidence of POF, PNec and in-hospital death, p values for trends across quartiles were <0.001, <0.001 and 0.043, respectively.

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Moreover, there was a positive trend for the association across increasing HDL-C quartiles and POF, PNec and mortality after multivariable analysis (p values were <0.001, <0.001 and 0.043, respectively).

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