Primary efficacy endpoint The change in adjusted mean QMG score from baseline to week 24 was larger in patients receiving tacrolimus versus placebo (–4.9 versus –3.3, respectively) ( Figure 2 ), but the difference did not reach statistical significance [least squares (LS) mean difference: –1.7; 95% CI: –3.5 to 0.1; p = 0.067).
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Tacrolimus in the treatment of myasthenia gravis in patients with an inadequate response to glucocorticoid therapy: randomized, double-blind, placebo-controlled study conducted in China.
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0.0670