Intervention Now to Eliminate Repeat Unintended Pregnancy in Teenagers (INTERUPT): a systematic review of intervention effectiveness and cost-effectiveness, and qualitative and realist synthesis of implementation factors and user engagement.

However, when four larger, but lower quality studies [ 47 , 58 , 59 ] were included in the sensitivity analysis of the primary outcome (unintended repeat pregnancy), the estimate approached but did not reach statistical significance: event rates of 288 of 1077 (27%) in the intervention arm and 297 of 1004 (30%) in the control arm, giving an RR of 0.88 (95% CI 0.78–1.00).

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