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Inflammatory microRNA-194 and -515 attenuate the biosynthesis of chondroitin sulfate during human intervertebral disc degeneration.

Oncotarget · 2017 · PMC5564769 · PMID 28514734

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Results showed that only the mRNA level of ACAN was significantly decreased in severe IDD compared to mild IDD group (Figure 2F–2K ), while differences in XYLT-1 , B4GALT7 , C4ST-1 , C6ST-1 , and HYAL-1 between the mild and severe IDD group did not reach statistical significance.

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