Changes in CKD-MBD parameters Changes in serum FGF23 levels The percentage change in the serum FGF23 level showed a trend to increase more in the combination group (calcium carbonate and calcitriol) than that in the calcitriol-alone group, although the difference was not statistically significant (with and without calcium carbonate: ΔFGF23 [%] =68.9%±58.8% and 35.1%±39.1%, respectively, P =0.097; Table 2 ).
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Effect of additive calcium administration on FGF23 levels in patients with mild chronic kidney disease treated with calcitriol: a randomized, open-labeled clinical trial.
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