a strong trendP = 0.0507
retrospectively analyzed the data from dose-escalation trial RTOG 9406 and found a strong trend toward improved disease-free survival associated with long-term ADT ( P = 0.0507) in patients with PSA >20 who received a cumulative RT dose above 73.8 Gy. 14 A review by Feng et al . of the results of DERT (75–79.2 Gy) in patients with high-risk prostate cancer 13 found that addition of ADT decreased the 5-year cumulative incidence of biochemical failure and distant metastases (35% vs 13%, P < 0.001).