High-density lipoproteins suppress Aβ-induced PBMC adhesion to human endothelial cells in bioengineered vessels and in monoculture.

Mol Neurodegener · 2017 · PMC5568306 · PMID 28830501

Europe PMC DOI

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0.0600

closest p · 1.2× alpha

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boldest claim

The sentences

a strong trendp = 0.06so close (0.05 < p ≤ 0.1)

Although total ICAM-1 levels showed no significant change in response to either Aβ40 or Aβ42 treatment, biotinylation assays revealed significantly increased cell surface ICAM-1 levels, but not VCAM-1 levels, in response to 0.1 μM of Aβ40 ( p = 0.009) and a strong trend in response to Aβ42 ( p = 0.06) (Additional file 6 h–j).

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